n 教育、进修经历 2001.9-2004.6江西中医药大学、硕士 2004.9-2007.6中国药科大学、博士 2008.4-2009.6美国路易斯安那州立大学、博士后 2014.1-2015.8美国路易斯安那州立大学、博士后 2007.6-2018.12广州中医药大学、副教授、教授 n 代表性科研项目 1. 国家药品监督管理局药品快速检验技术重点实验室开放课题“基于质谱分子网络技术探讨何首乌生熟异治的药效物质基础差异与炮制方法的相关性”，2022/01-2024/12，8万元，主持，在研。 2. 国家自然科学基金青年科学基金项目，81403061，基于PK-PD与代谢组学方法研究何首乌肝毒性的毒效物质与致毒机理，2015/01-2017/12，23万元，主持，结题。 3.广州中医药大学青年英才项目QNYC20140108，何首乌药材中二苯乙烯苷类化合物的体内代谢规律研究，2014/10-2018/10，20万元，主持，结题。 n 代表性论文、著作等 1. He, X., Liu, J., Long, G., Xia, X. H., &Liu, M. (2021). 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-gluco side, a major bioactive component from Polygoni multiflori Radix (Heshouwu) suppresses DSS induced acute colitis in BALb/c mice by modulating gut microbiota. Biomedicine & pharmacotherapy, 137, 111420. https://doi.org/10.1016/j.biopha.2021.111420 2.Xia, X. H., Yuan, Y. Y., &Liu, M. (2017). The assessment of the chronic hepatotoxicity induced by Polygoni Multiflori Radix in rats: A pilot study by using untargeted metabolomics method. Journal of ethnopharmacology, 203, 182–190. https://doi.org/10.1016/j.jep.2017.03.046 3.Zhang, J., Chou, G., Liu, Z., &Liu, M. (2016). Employing rubusoside to improve the solubility and permeability of antitumor compound betulonic acid. Nanomedicine (London, England), 11(21), 2829–2844. https://doi.org/10.2217/nnm-2016-0188 4.Xia, X. H., Li, Q., &Liu, M. (2014). Neuroprotective effect of a formula, moschus combined with borneolum synthcticum, from traditional chinese medicine on ischemia stroke in rats. Evidence-based complementary and alternative medicine: eCAM, 2014, 157938. https://doi.org/10.1155/2014/157938 5.Liu, M., Xia, X., Chou, G., Liu, D., Zuberi, A., Ye, J., & Liu, Z. (2014). Variations in the contents of gingerols and chromatographic fingerprints of ginger root extracts prepared by different preparation methods. Journal of AOAC International, 97(1), 50–57. https://doi.org/10.5740/jaoac int.12-437 6.Liu, M., Li, Y., Chou, G., Cheng, X., Zhang, M., & Wang, Z. (2007). Extraction and ultra-performance liquid chromatography of hydrophilic and lipophilic bioactive components in a Chinese herb Radix Salviae Miltiorrhizae. Journal of chromatography. A, 1157(1-2), 51–55. https://doi.org/10.1016/j.chroma.2007.05.018 7.Liu, M., Li, Y. G., Zhang, F., Yang, L., Chou, G. X., Wang, Z. T., & Hu, Z. B. (2007). Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS). Journal of separation science, 30(14), 2256–2267. https://doi.org/10.1002/jssc.200700149 n 教学科研获奖情况 1. 发明专利,刘梅，尹永芹.白鹤藤中总黄酮和奎宁酸酯类化合物的提取与富集方法.ZL202010035561.0 |
