n 教育经历： [1] 2010-10 至 2014-06，河南农业大学，动物医学，学士 [2] 2014-09 至 2019-06，华南农业大学，临床兽医，博士 n 代表性科研项目 [1] 广州市科技局基础研究计划，环氧化物酶2偶联NLRP3炎性小体在猪瘟病毒诱导炎症中的作用机制研究，2023.04- 2025.04，主持； [2] 国家自然科学基金委员会，面上项目，感染犬流感病毒的宿主miRNAs和mRNAs数据可构建及RIG-I样通路研究，2017.01-2020.12，研究骨干； [3] 国家自然科学基金委员会，面上项目，H3N2亚型禽流感病毒跨种传播感染猫的分子机制研究，2018.01-2021.12，研究骨干； n 代表性论文 [1] W. Zhu, S. Zeng, S. Zhu, Z. Zhang, R. Zhao, Q. Qiu, Z. Luo, Y. Qin, W. Chen, B. Li, Y. He, L. Yi, H. Ding, M. Zhao, J. Chen, ChengFu*, and S. Fan*, Histone H2B lysine lactylation modulates the NF-kappaB response via KPNA2 during CSFV infection. International journal of biological macromolecules 299 (2025) 139973. [2] S. Zeng, Z. Luo, W. Zhu, Z. Zhang, R. Zhao, S. Zhu, Q. Qiu, N. Cao, X. Fu, W. Liu, S. Fan, and ChengFu*, LDHA-lactate axis modulates mitophagy inhibiting CSFV replication. Journal of virology 99 (2025) e0026825. [3] ChengFu, W. Zhu, N. Cao, W. Liu, Z. Lu, Z. Wong, K. Guan, C. Hu, B. Han, S. Zeng, and S. Fan, Role of CIV NS1 Protein in Innate Immunity and Viral Replication. International journal of molecular sciences 24 (2023). [4] ChengFu, N. Cao, S. Zeng, W. Zhu, X. Fu, W. Liu, and S. Fan, Role of mitochondria in the regulation of ferroptosis and disease. Frontiers in medicine 10 (2023) 1301822. [5] ChengFu, N. Cao, W. Liu, Z. Zhang, Z. Yang, W. Zhu, and S. Fan, Crosstalk between mitophagy and innate immunity in viral infection. Frontiers in microbiology 13 (2022) 1064045. [6] ChengFu, S.T. Ye, Y.B. Liu, and S.J. Li, Role of CARD Region of MDA5 Gene in Canine Influenza Virus Infection. Viruses-Basel 12 (2020). [7] ChengFu, J. Luo, S. Ye, Z. Yuan, and S. Li, Integrated Lung and Tracheal mRNA-Seq and miRNA-Seq Analysis of Dogs with an Avian-Like H5N1 Canine Influenza Virus Infection. Frontiers in microbiology 9 (2018) 303. [8] Z. Wang, S.T. Ye, C.W. Yao, J. Wang, J.W. Mao, L. Xu, Y.B. Liu, ChengFu, G. Lu, and S.J. Li, Antiviral Activity of Canine RIG-I against Canine Influenza Virus and Interactions between Canine RIG-I and CIV. Viruses-Basel 13 (2021). [9] Y. Liu, ChengFu, S. Ye, Y. Liang, Z. Qi, C. Yao, Z. Wang, J. Wang, S. Cai, S. Tang, Y. Chen, and S. Li, The inactivated vaccine of reassortant H3N2 canine influenza virus based on internal gene cassette from PR8 is safe and effective. Veterinary microbiology 254 (2021) 108997. [10] Y. Liu, ChengFu, S. Ye, Y. Liang, Z. Qi, C. Yao, Z. Wang, J. Wang, S. Cai, S. Tang, Y. Chen, and S. Li, Phosphoproteomics to Characterize Host Response During H3N2 Canine Influenza Virus Infection of Dog Lung. Frontiers in veterinary science 7 (2020) 585071. [11] Y. Liu, ChengFu, G. Lu, J. Luo, S. Ye, J. Ou, X. Wang, H. Xu, J. Huang, L. Wu, X. Zhang, P. Wu, and S. Li, Comparison of Pathogenicity of Different Infectious Doses of H3N2 Canine Influenza Virus in Dogs. Frontiers in veterinary science 7 (2020) 580301. [12] J. Luo, G. Lu, S. Ye, J. Ou, C. ChengFu. Zhang, X. Wang, J. Huang, P. Wu, H. Xu, L. Wu, and S. Li, Comparative pathogenesis of H3N2 canine influenza virus in beagle dogs challenged by intranasal and intratracheal inoculation. Virus Res 255 (2018) 147-153. [13] G. Lu, ChengFu, J. Huang, H. Xu, P. Wu, X. Ping, and S. Li, Molecular characterization of a genetically divergent equine pegivirus strain identified in China. Archives of virology 163 (2018) 249-252. [14] P. Zhou, L. Wang, S. Huang, ChengFu, H. He, M. Hong, S. Su, and S. Li, Beagle dogs have low susceptibility to BJ94-like H9N2 avian influenza virus. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 31 (2015) 216-20. [15] P. Zhou, X. Fu, Z. Yan, B. Fang, S. Huang, ChengFu, M. Hong, and S. Li, Antiviral effect of lithium chloride on infection of cells by canine parvovirus. Archives of virology 160 (2015) 2799-805. [16] L. Sun, P. Zhou, S. He, Y. Luo, K. Jia, ChengFu, Y. Sun, H. He, L. Tu, Z. Ning, Z. Yuan, H. Wang, S. Li, and L. Yuan, Sparse serological evidence of H5N1 avian influenza virus infections in domestic cats, northeastern China. Microbial pathogenesis 82 (2015) 27-30. [17] 付橙; 范双旗; 猪瘟病毒感染细胞后线粒体代谢变化的组学分析, 仲恺农业工程学院学报, 2026, [18] 洪马林, 付橙, 黄三, 周沛, 粟硕, 李守军: 广州地区猫泛白细胞减少症病毒分离鉴定及全基因组遗传分析. 华南农业大学学报 2017, 38(01):9-14. [19] 闫中山, 洪马林, 付橙, 黄三, 郑运, 王丽芳, 周沛, 粟硕, 李守军: 一株H3N2亚型犬流感病毒的分离鉴定及遗传进化分析. 中国预防兽医学报 2016, 38(05):407-409. [20] 赵苗苗, 王丽芳, 黄三, 付橙, 罗永峰, 孙彦阔, 陈智华, 李守军: 广东1株H3N2亚型犬流感病毒全基因组遗传进化分析. 中国兽医学报 2016, 36(10):1696-1700. |
