n 教育和工作背景 2014.09-2018.06：华南农业大学，动物科学学院生理学专业 理学博士 2011.09-2014.07：仲恺农业工程学院，轻工食品学院农产品加工及贮藏工程专业 农学硕士 2007.09-2011.07：仲恺农业工程学院，生命科学学院动物科学（检验检疫）专业 农学学士 n 代表性科研项目（经费主持共计100多万） 主要从事中药多糖等饲料添加剂对畜禽生长发育及免疫功能调节作用的相关研究。 ⑴ 广东省基础与应用基础研究基金区域联合基金-青年基金项目：Novel-mir2在白术多糖维持免疫抑制雏鹅T细胞活化水平中的机制研究 ⑵国家自然科学基金-青年科学基金项目：白术多糖通过novel-mir2双靶向TRADD/MLKL缓解免疫抑制雏鹅的胸腺程序性坏死 n 代表性教学项目 动物营养学，动物营养与饲料学大实验 n 代表性论文 1、Wanyan Li, Sixuan Guo, Danning Xu, Bingxin Li, Nan Cao, Yunbo Tian, Qingyan Jiang. Polysaccharide of Atractylodes macrocephala Koidz (PAMK) Relieves Immunosuppression in Cyclophosphamide-Treated Geese by Maintaining a Humoral and Cellular Immune Balance[J]. Molecules, 2018, 23(4):932-947 2、Wanyan Li, Danning Xu, Bingxin Li, Nan Cao, Sixuan Guo, Qingyan Jiang, Yunbo Tian.The polysaccharide of Atractylodes macrocephala koidz (PAMK) alleviates cyclophosphamidemediated immunosuppression in geese, possibly through novel_mir2 targeting of CTLA4 to upregulate the TCR-NFAT pathway[J]. RSC Adv., 2018, 8, 26837–26848 3、李婉雁，曹楠，田允波，相雪莲，李冰心，黄运茂，许丹宁.白术多糖通过Toll 样受体4/核因子κB信号通路调控雏鸡脾脏淋巴细胞免疫功能。动物营养学报，2019，31( 11) : 5192-5201 4、Xuelian Xiang, Nan Cao, Feiyue Chen, Long Qian, Yifei Wang, Yunmao Huang, Yunbo Tian, Danning Xu and Wanyan Li. Polysaccharide of Atractylodes macrocephala Koidz (PAMK) Alleviates Cyclophosphamide-induced Immunosuppression in Mice by Upregulating CD28/IP3R/PLCγ-1/AP-1/NFAT Signal Pathway. Frontiers in Pharmacology.Doi: https://doi.org/10.3389/fphar.2020.529657. 5、Wanyan Li, Xuelian Xiang, Bingxin Li, Yifei Wang, Long Qian, Yunbo Tian, Yunmao Huang, Danning Xu, and Nan Cao. PAMK Relieves LPS-Induced Enteritis and Improves Intestinal Flora Disorder in Goslings. Evidence-Based Complementary and Alternative Medicine. Doi.org/10.1155/2021/9721353. 6、Wanyan Li, Xuelian Xiang, Nan Cao, Wenbin Chen,Yunbo Tian, Xumeng Zhang, Xu Shen, Danli Jiang, Danning Xu, Shiwen Xu. Polysaccharide Of Atractylodes Macrocephala Koidz activated Tlymphocytes to alleviate cyclophosphamide-induced immunosuppression of geese through novel_mir2/CD28/AP-1 signal pathway. Poultry Science. https://doi.org/10.1016/j.psj.2021.101129. 7、Wanyan Li,Xiangying Zhou,Shiwen Xu,Nan Cao,Bingxin Li,Wenbin Chen,Baohe Yang,Mingfeng Yuan, and Danning Xu. Lipopolysaccharide-induced splenic ferroptosis in goslings was alleviated by polysaccharide of atractylodes macrocephala koidz associated with proinflammatory factors. Poult Sci. 2022 May; 101(5): 101725. doi: 10.1016/j.psj.2022.101725 8、陈丽君,李冰心,曹楠,付新亮,杨保和,袁明凤,许丹宁,田允波,黄运茂,李婉雁.白术多糖通过线粒体和死亡受体途径缓解脂多糖诱导的雏鹅胸腺细胞凋亡[J].动物营养学报,2022,34(12):8049-8060. n 专利 1、李婉雁.动物信息标记追溯管理系统V1.0，2017，中国，已授权，专利号：2017SR622156 2、李婉雁.冻存生物样本库资源管理信息系统V1.0, 2019，中国，已授权，专利号：2019SR0952050 3、李婉雁,李冰心,曹楠.生物样本冷藏信息化集成管理系统V1.0，2020，中国，已授权，专利号：2020SR0423529 4、李婉雁,李冰心,曹楠.家禽养殖类安全追溯与监管软件V1.0，2020，中国，已授权，专利号：2020SR0423832 n 获奖 获得教学等方面的荣誉多项，如“十佳中青年教师”、“教学质量优秀奖三等奖”、指导学生参与“雄鹰杯”小动物医师技能大赛并获得“优秀辅导老师奖”。 |
