工学博士，中共党员，研究生导师。目前主持或参与各级项目8项，其中主持国家级基金及省级项目各1项；发表学术论文共42篇，其中SCI论文34篇，以第一作者或通讯作者在 Environmental Pollution、Ecotoxicology and Environmental Safety、Frontiers in Immunology、Journal of Environmental Chemical Engineering、Aquatic Toxicology、Aquaculture、Fish & Shellfish Immunology、Journal of Fish Diseases、Developmental and Comparative Immunology等杂志发表SCI论文23篇、中文核心3篇；获授权专利2项。 教育背景： 2009.9-2014.7 中国科学院烟台海岸带研究所环境科学专业，获工学博士学位 2005.9-2009.7 广东海洋大学海洋科学专业，获理学学士学位 工作经历： 2025.1-至今 仲恺农业工程学院，副教授 2019.9 -2024.12 仲恺农业工程学院，讲师 2014.7-2015.8 中国科学院南海海洋研究所，博士后 研究领域： 1. 水产动物肠道微生物协同机制 2. 微生态制剂的研发 3. 水产动物营养免疫与肠道屏障调控机制 承担科研项目情况： 1. 国家自然科学基金青年科学基金项目；4210061024；哈维弧菌对珍珠龙胆石斑鱼肠道菌群的调控及壳寡糖的干预机制研究；2022.01-2024.12；30万，结题，主持； 2. 广东省驻镇帮扶村农村科技特派员；2024.07-2027.07；24万，在研，主持； 3. 广东省驻镇帮扶村农村科技特派员；2022.01-2024.12；30万，，结题，参与； 4. 水产动物苗种提质抗病高效开口配合饲料研发；D123222H802；2026.4-2028.4；5.5万，在研，主持； 5. 海南省热带水生生物技术重点实验室开放课题；SWJS202404；咄虫酰胺对凡纳对虾幼体发育的毒性效应研究；2024.11-2025.10，1.5万，结题，主持； 6. 中国科学院热带海洋生物资源与生态重点实验室联合资助开放课题；LMB20200104；壳寡糖对石斑鱼生长、免疫及菌群调剂的机制研究；2021.01-2022.12；5万，结题，主持； 7. 广州瑞森生物科技股份有限公司横向课题；D12122238；五种水产鱼病抗原及抗体制备； 2021.01-2021.12，10万，结题，主持； 8. 仲恺农业工程学院年薪制人员科研启动费；KA200540866；芽孢杆菌对草鱼的免疫及肠道菌群的机制研究；2019.10-2021.12；8万，结题，主持。 代表性论著： 1. Ma Lixin, Tan Junyuan, Zheng Xiaomin, He Zhuojin, Qin Zhendong, Lin Li, Shi Fei*. Microcystis aeruginosa-driven acute toxicity compromises immune–metabolic regulation and hepatocyte integrity in grass carp. ![]() Environmental Pollution. 2026. 398:128088. (JCR 1区, IF=7.3) 2. Ma Lixin, Chen Zhilong, He Zhuojin, Zheng Xiaomin, Li Yutao, Zhou Cuiyun, Lin Li*, Shi Fei*. Protective role of oligochitosan in intestinal homeostasis to Edwardsiella ictaluri in hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂). Aquaculture. 2025. 610:742923. (JCR 1区, IF=4.242) 3. Ma Lixin, Chen Zhilong, He Zhuojin, Zheng Xiaomin, Li Jiajia, Zou Cuiyun, Lin Li*, Shi Fei*. Modulation of hepatic immune-metabolic pathways by oligochitosan in hybrid grouper infected with Edwardsiella ictaluri. Fish & Shellfish Immunology. 2025, 167:110657. (JCR 1区, IF=4.581) 4. Ma Lixin, Tan Junyuan, Zheng Xiaomin, He Zhuojin, Qin Zhendong, Lin Li, Shi Fei*. Microcystin-LR disrupts gut metabolic homeostasis through microbiota–metabolite axis remodeling in grass carp. Comparative Biochemistry and Physiology, Part C. 2026, 306:110524. (JCR 1区, IF=4.3) 5. He Zhuojin#, Zheng Xiaomin#, Ma Lixin, Chen Zhilong, Lin Li, Shi Fei*. Acute intestinal injury in hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂) under infection with Vibrio harveyi. Developmental and Comparative Immunology. 2025, 173:105525. (JCR 1区, IF=4.242) 6. Shi Fei#, Chen Zhilong#, Yao Minshan#, Huang Yao, Xiao Jin, Ma Lixin, Mo Jilin, Lin Li*, Qin Zhendong*. Effects of glutaraldehyde and povidone-iodine on apoptosis of grass carp liver and hepatocytes. Ecotoxicology and Environmental Safety. 2024, 272: 116078. (JCR 1区, IF=6.8). 7. Shi Fei, Ma Lixin, Chen Zhilong, Huang Yao, Lin Li*, Qin Zhendong*. ![]() Long-term disinfectant exposure on intestinal immunity and microbiome variation of grass carp. Aquatic Toxicology. 2024, 272:106924. (JCR 1区, IF=4.5). 8. Shi Fei#, Yao Minshan#, Huang Yao, Chen Zhilong, Xiao Jin, Zhan Fanbin, Li Yanan, Lin Li, Qin Zhendong. Effects of antibiotics on immunity and apoptosis on grass carp liver and hepatocytes. Journal of Environmental Chemical Engineering. 2023, 11(3):110168. (JCR1区，IF=7.968) 9. Shi Fei, Huang Yao, Yang Mingxuan, Lu Zhijie, Li Yanan, Zhan Fanbin, Li Lin*, Qin Zhendong*. Antibiotic-induced alternations in gut microflora are associated with the suppression of immune-related pathways in grass carp (Ctenopharyngodon idellus). Frontiers in Immunology. 2022, 13: 950125. (JCR1区，IF=8.786) 10. Shi Fei, Lu Zhijie, Yang Minxuan, Li Feng, Zhan Fanbin, Zhao Lijuan, Li Yanan, Li Qingqing, Li Jiangtao, Li Jun, Lin Li*, Qin Zhendong*. Astragalus polysaccharides mediate the immune response and intestinal microbiota in grass carp (Ctenopharyngodon idellus). Aquaculture. 2020, 534: 736205. (JCR 1区, IF=4.242) 11. Shi Fei#, Zi Yingjuan #, Lu Zhijie, Yang Minxuan, Zhan Fanbin, Li Jun, Zhao Lijuan, Lin Li*, Qin Zhendong*. Bacillus subtilis H2 modulates immune response, fat metabolism and bacterial flora in the gut of grass carp (Ctenopharyngodon idellus). Fish & Shellfish Immunology. 2020, 106: 8-20. (JCR 1区, IF=4.581) 12. Shi Fei#, Qiu Xiaolong#, Nie Lingju, Hu Luoying, Sarath Babu V., Qiang Lin, Zhang Yulei, Chen Liehuan, Lin Li*, Qin Zhendong*. Effects of oligochitosan on the growth, immune responses and gut microbes of tilapia (Oreochromis niloticus). Fish & Shellfish Immunology. 2020, 106: 563-573. (JCR 1区, IF=4.581) 13. 施斐, 黄垚, 卢志杰, 邹翠云, 谭小红, 苏友禄, 汤开浩, 秦真东*, 林蠡*. 壳寡糖对虎龙斑的生长、免疫及肠道菌群的影响. 2022, 46(9):1-13. 专利： 施斐. 壳寡糖对石斑鱼生长实时记录软件V1.0，2022，软件著作权专利，已授权，登记号：2022SR0882043. 施斐. 鱼类肠道微生物作用综合分析系统V1.0，2022，软件著作权专利，已授权，登记号：2022SR0877409. |
