n 简历 博士，研究员，南昌大学和湖南农业大学硕士生导师。2005年7月毕业于华中农业大学；2010年在中国科学院大学获得理学博士学位，导师印遇龙研究员。毕业后在中国科学院亚热带农业生态所先后任创新助理研究员和副研究员；期间在南昌大学生命科学与食品工程学院从事博士后研究，2013-2014年在法国国家农业科学研究院（INRA）访问学者。 主要研究母体与子代氨基酸、核苷酸、微量元素的营养代谢与生理功能的联系，先后主持十三五国家重点研发计划课题、十二五国家科技支撑计划子课题、国家自然科学基金青年基金等多项。在国内外公开发表学术论文150多篇，其中以第一作者或通讯作者发表论文SCI收录60多篇，国内外会议论文收录32篇，参编专著5部，申请国家发明专利22项，授权16项。以前三完成人获国家自然科学奖二等奖、中国科学院科技促进发展奖、中华农业科技奖一等奖和湖南省发明奖一等奖等省部级奖8项。 入选国家创新人才推进计划中青年科技创新领军人才（2017年）、湖南省121创新人才工程第三层次人选等。 主要社会兼职：中国农学会理事、微量元素与食物链分会秘书长、中国生物物理学会生物微量元素分会理事、中国畜牧兽医学会家畜生态学分会理事。 研究方向：母体与子代氨基酸、核苷酸、微量元素和饲用植物及其提取物的营养代谢；营养与生物钟；畜禽健康和环境因子等。 n 承担科研项目 近五年主持项目：十三五国家重点研发计划课题、十二五国家科技支撑计划子课题项目、中科院科技服务网络计划(STS计划)项目、国家自然科学基金、湖南省重大专项子项目、大型企业联合研发合作项目（功能性饲料添加剂关键技术的研究与产业化、酵母核苷酸的研究与应用等）、中国科学院国际人才计划等。 n 代表论著 代表论著（*为通讯作者）： 1.Yuebang Yin, Songge Guo, Dan Wan, Xin Wu*, and Yulong Yin. Enteroids: promising in vitro models for studies of intestinal physiology and nutrition in farm animals. Journal of Agricultural and Food Chemistry, 2019, DOI: 10.1021/acs.jafc.8b06908 2.Yin Jie, Yuying Li, Hui Han, Shuai Chen, Jing Gao, Gang Liu, Xin Wu*, Jinping Deng, Xingguo Huang, Rejun Fang, Tiejun Li*, Russel J. Reiter, Guoqiang Zhu, Wenkai Ren*, Yulong Yin. Melatonin improves lipid metabolism by reprograming gut microbiota and microbiota-derived acetic acid. Journal of Pineal Research, 2018:e12524, DOI: 10.1111/jpi.12524 3.Xin Wu, Chunyan Xie, Cimin Long, Jun Li, Xihong Zhou, Zhiyong Fan, Francois Blachier, Yulong Yin*. Effects of a daily 3-meal pattern with different dietary protein contents on pig growth performance, carcass and muscle quality traits. Journal of the Science of Food and Agriculture, 2018, 98(1): 415–421 4.Liu Yi-lin, Wan Dan, Xihong Zhou, Ruan Zheng, Xin Wu*, Yulong Yin. Dynamic feeding of methionine rhythmically influences glucose and lipid metabolism in the liver of laying hens. Poultry Science, 2019, DOI: 10.3382/ps/pey589 5.Xin Wu, Lumin Gao, Kai Zhou, Xue Li, Xue Lin, Dan Wan, Xia Xiong, Gang Liu, Yulong Yin*. Deposition and transport of trace mineral elements were affected by stocking density in fattening pigs. Journal of Trace Elements in Medicine and Biology, 2018, 50：566-571 6.Xihong Zhou, Yumei Zhang, Xin Wu*, Dan Wan, Yulong Yin*. Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets. Cellular Physiology and Biochemistry, 2018，48:993–1002 7.Xue LIN, Yilin LIU, Tiantian MENG, Chunyan Xie, Xin Wu*, Yulong YIN. Circadian calcium feeding regime in laying hens related to zinc concentration, gene expression of circadian clock, calcium transporters and oxidative status.Journal of Trace Elements in Medicine and Biology, 2018, 50：518-526 8.Xihong Zhou, Haiwen Zhang, Liuqin He, Xin Wu*, Yulong yin. Long-term L-serine administration reduces food intake and improves oxidative stress and Sirt1/NFκB pathway in the hypothalamus in aging mice. Frontiers in Endocrinology,2018,9:476 9.Dan Wan, Y. M. Zhang, X. Wu*, X. Lin, X. G. Shu, X. H. Zhou, W.G. Xing, H. N. Liu, L. Li, Y. Li, H. T. Du, Yulong Yin*. Maternal dietary supplementation with ferrous N-carbamylglycinate chelate affects sow reproductive performance and iron status of neonatal piglets. Animal, 2018, 12(7):1372-1379 (1区) 10.Xihong Zhou, Liuqin He, Shengnan Zuo, Yumei Zhang, Ciming Long, Pan Huang, Canrong Wu, Gang Liu, Wu Xin*, Yulong Yin*. Serine attenuates high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes. BBA-Molecular Basis of Disease, 2018, 1864：488–498 . (1区, IF5.48) 11.Tiantian MENG, Yi-lin LIU, Chun-yan XIE*, Bin Zhang, Yiqiang Huang, Ya-wei Zhang, Yajun Yao, Ruilin Huang, Xin Wu*. Effects of Different Selenium Sources on Laying Performance, Egg Selenium Concentration, and Antioxidant Capacity in Laying Hens. Biological Trace Element Research, 2018, DOI: 10.1007/s12011-018-1490-z 12.Liu Yi-lin, Zhang Ke, Zhou Xi-hong, Wan Dan, Ruan Zheng, Xin Wu*, Yulong Yin*. Dynamic feeding low and high methionine diets affect the diurnal rhythm of amino acid transporters and clock related genes in jejunum of laying hens. Biological Rhythm Research, 2018, 49(5):671-679 13.Xue Lin, Yi Liu, Xin Wu, Yin Yulong. dynamic feeding low and high Ca diets on egg quality traits in laying hens. Biological Rhythm Research, 2018, 49:2, 227-236. 14.Ke Zhang, Yi-lin Liu, Yumei Zhang, Juan Zhang, Zeyuan Deng, Xin Wu, Yulong Yin. Dynamic oral administration of uridine affects the diurnal rhythm of bile acid and cholesterol metabolism related genes in mice. Biological Rhythm Research, 2018, DOI: 10.1080/09291016.2018.1474844 15.Lan Li, Shuai Chen, Xue Li, Dan Wan, Gang Liu*, Yi Liu,Xiangfeng Kong*, Xia Xiong, Xin Wu*, Sung Woo Kim, Yin Yulong. Intestinal microbiota in growing pigs: effects of stocking density. Food and Agricultural Immunology, 2018, 29: 524-535 16.Wu Xin, Chunyan Xie*, Xiaoyun Guo, Cimin Long, Tianyong Zhang, Tianzeng Gao, Yulong Yin*. A Maternal meal Feeding Pattern with Varying Crude Protein Affacted Milk Lipid Profile in A Sow-Piglet Model. Scientific Reports, 2017, 7：13742 17.Xihong Zhou, Liuqin He, Canrong Wu, Yumei Zhang, Xin Wu*, Yulong Yin. Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice. Molecular Nutrition & Food Research, 2017, 61（11）：1700262 18.Liu Y., Lin X., Zhou Xihong, Wan Dan, Wu Xin*, Yin Yulong. Effects of dynamic feeding low and high methionine diets on egg quality traits in laying hens. Poultry Science, 2017, 96(5): 1459-1465 19.Xihong Zhou, Yumei Zhang, Liuqin He, Dan Wan, Gang Liu, Xin Wu, Yulong Yin. Serine prevents LPS-induced intestinal inflammation and barrier damage via p53-dependent glutathione synthesis and AMPK activation. Journal of Functional Foods, 2017, 39: 225–232 20.Wan Dan, Liu Yi-lin, Li Guan-ya, Huang Rui-lin, Zhang Yi-ming, Long Ci-min, Ruan Zheng, Li Lan, Wu Xin*, Zhou Xi-hong*, Yin Yu-long*. Circadian regulation of the hepatic transcriptome and circulating nutrient levels with laying hen as a model. Oncotarget, 2017, 8（69）:113885-113894 21.Hongnan Liu, Kang Xu, Gang Liu, Xiangfeng Kong, Xin Wu*, Yulong Yin*. Short-term supplementation ofisocaloric meals with L-tryptophan affects pig growth. Amino acids, 2017, 48（7）：1533-1540 22.Zhang Y, Wan D, Zhou X, Long C, Wu X, Li L, He L, Huang P, Chen S, Tan B, Yin Y. Diurnal variations in iron concentrations and expression of genes involved in iron absorption and metabolism in pigs. Biochem Biophys Res Commun. 2017, 490(4):1210-1214. 23.Dengbo, Xihong Zhou, Wu Jie, Cimin Long, Yao Yajun, Peng Hongxing, Wan Dan, Xin Wu*. Effects of dietary supplementation with tribasic zinc sulfate or zinc sulfate on growth performance, zinc content and expression of zinc transporters in young pigs. Animal Science Journal, 2017, 88(10):1556-1560 24.Xihong Zhou, Dan Wan*, Yumei Zhang, Yiming Zhang, Cimin Long, Shuai Chen, Liuqin He, Bie Tan, Xin Wu*, Yulong Yin*. Diurnal variations in polyunsaturated fatty acid contents and expression of genes involved in their de novo synthesis in pigs. Biochemical and Biophysical Research Communications, 2017, 483: 430-434 25.Yumei Zhang, Xihong Zhou, Bin Zhang*, Xin Wu*, Yulong Yin. Diurnal Rhythm in mRNA Expression of Genes encoding Amino Acid Transporter and Circadian Gene Cry in Intestinal Mucosa of Piglets. Biological Rhythm Research, 2017, 48(4):663-671 26.Kang Xu, Hongnan Liu, Miaomiao Bai, Jing Gao, Xin Wu, Yulong yin*. Antioxidant activities of tryptophan metabolism and the concept of tryptophan use in pregnancy. International Journal of Molecular Sciences, 2017, 24;18(7): E1595 27.Xin Wu, Chunyan Xie, Xihong Zhou ?, Dan Wan,Yulong Yin. Selenium yeast normalizes male rats from glutamate-induced Kiss/GPR54 abnormity in brain and testis. Journal of Trace Elements in Medicine and Biology, 2017, 41S:74 (Abstract) 28.Xin Wu, Chunyan Xie, Xihong Zhou, Dan Wan, Yulong Yin ?. Effects of Selenium Yeast in the setting of glutamate-induced Kiss/GPR54 normalizes in ovary of pregnant rats. Journal of Trace Elements in Medicine and Biology, 2017, 41S:84 (Abstract) 29.Wu Xin, Chunyan Xie, Zhang Yuzhe, Fan Zhiyong, Y.L. Yin, F. Blachier. Glutamate–glutamine cycle and exchange in the placenta–fetus unit during late pregnancy. Amino acids, 2015, 47, (1): 45-53. 30.Yi Liu, Xue Lin, Xihong Zhou, Dan Wan, Xin Wu*, Yin Yulong. Effects of dynamic feeding low and high methionine diets on egg quality traits in laying hens. Poultry Science, 2016, doi: 10.3382/ps/pew398 31.Chunyan Xie, Xin Wu*, Xiaoyun Guo, Cimin Long, Siming Li, Chien-An Andy Hu, Yin Yulong. Maternal chitosan oligosaccharide supplementation affecting expression of circadian clock genes, and possible association with hepatic cholesterol accumulation in suckling piglets. Biological Rhythm Research, 2016, 47(2): 253-265. 32.Xin Wu*, Chunyan Xie, Biao Li, Huiqi Zhou, Bin Tan, Juan Yao, Kui Li*, Zhiyong Fan, Bin Zhang, Lin Zhou, Yulong Yin. Effect of Yeast extract on growth performance and intestinal mucosa morphology of weanling piglets. Journal of Animal & Plant Sciences, 2016, 26(6): 1568-1575 33.Chunyan Xie, Xin Wu*, Cimin Long, Qinhua Wang, Zhiyong Fan, Siming Li, Yulong Yin*. Chitosan oligosaccharide affects antioxidant defense capacity and placental amino acids transport of sows. BMC Veterinary Research, 2016 12:243 34.Li Biao, Zhou Huiqi, Wu Xin*, Zhongping Chen, Juan Yao, Yulong Yin*. Effects of dietary supplementation with uridine monophosphate on performance and intestinal morphology of weanling piglets. Journal of Animal Science, 2016, 94:82–86 35.Chunyan Xie, Cimin Long, Xin Wu*, Zhiyong Fan, Yongfei Wang, Yulong Yin*. Effect of maternal supplementation with chitosan oligosaccharide on the antioxidant capacity in suckling piglets. Journal of Animal Science, 2016, 94: 453-456. 36.Xihong Zhou, Liuqin He, Dan Wan, Huansheng Yang, Kang Yao, Guoyao Wu, Xin Wu*, Yulong Yin*. Methionine restriction on lipid metabolism and its possible mechanisms. Amino acids, 2016, 48: 1533–1540 37.Chunyan Xie, Qinhua Wang, Jing Wang, Bie Tan, Zhiyong Fan, Zeyuan Deng, Xin Wu *, Yulong Yin *. Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period. Biochem Biophys Res Commun, 2016, 470(4): 824–830. 38.Yan Zhou, Lili Zhou, Zheng Ruan*, Shumei Mi, Min Jiang, Xiaolan Li, Xin Wu, Zeyuan Deng, Yulong Yin. Chlorogenic acid ameliorates intestinal mitochondrial injury by increasing antioxidant effects and activity of respiratory complexes. Bioscience, Biotechnology, and Biochemistry, 2016, 80(5):962-971. 39.Xu-gang Shu*, Chun-li Wu, Cui-jin Li, Min Zhang, Ke Wan, Xin Wu*. Synthesis, Crystal Structure and Spectroscopic Properties of Zn(II) With 2-Aminoethanethiol Hydrochloride Ligand. Bioinorganic Chemistry and Applications, 2016：2691253 40.Chunyan Xie, Qinhua Wang, Jing Wang, Bie Tan, Zhiyong Fan, Zeyuan Deng, Xin Wu *, Yulong Yin *. Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period. BBRC, 2016, 470(4): 824–830. 41.Xin Wu, Xiaoyun Guo, Chunyan Xie, Tianyong Zhang, Pengfei Gao, Tianzeng Gao, Yulong Yin. Effects of a two-meal daily feeding pattern with varied crude protein levels on growth performance and antioxidant indexes in pigs. Animal Science, 2016 (2): 267-270. 42.Wu Xin, Wan Dan, Xie Chunyan, Li Tiejun, Huang Ruilin, Shu Xugang, Ruan Zheng, Deng Zeyuan, Yin Yulong. Acute and sub-acute oral toxicological evaluations and mutagenicity of N-carbamylglutamate (NCG). Regulatory Toxicology and Pharmacology, 2015, 73 (1):296-302. 43.Yuzhe Zhang, Xiaoming Sun?, Chunyan Xie?, Xugang Shu, OSO Abimbola Oladele, Zheng Ruan, Ze-yuan Deng, Xin Wu*, Yin Yulong. Effects of ferrous carbamoyl glycine on iron state and absorption in an iron-deficient rat model. Gene & Nutrition, 2015, 10:54 44.Xie Chunyan, Guo Xiaoyun, Long Cimin, Fan Zhiyong, Ruan Zheng, Deng Ze-yuan, Xiao Dingfu, Wu Xin*, Yin Yulong*. Supplementation of the sow diet with chitosan oligosaccharide during late gestation and lactation affects hepatic gluconeogenesis of suckling piglets. 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Dietary supplementation with yeast extract at different times affected growth performance and plasma amino acids of growing pigs. Amino Acids (2015) 47: 1684 50.Xiong X, Yang HS, Wang XC, Hu Q, Liu CX, Wu X, Deng D, Hou YQ, Nyachoti CM, Xiao DF, Yin YL. Effect of low dosage of chito-oligosaccharide supplementation on intestinal morphology, immune response, antioxidant capacity, and barrier function in weaned piglets. J Anim Sci. 2015 Mar;93(3):1089-97 51.Duan JL, Yin J, Ren WK, Wu MM, Chen S, Cui ZJ, Wu X, Huang RL, Li TJ, Yin YL. Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide. Free Radic Res. 2015, 49(2):210-8. 52.Xu-gang Shu*, Chun-li Wu, Ke Wan, Min Zhang, Xin Wu. Synthesis, Crystal Structure and Spectroscopic Properties of Zn(II) with N-carbamylglutamate Ligand. Chinese J. Struct. Chem.，2015，34（04）：619-627 53.Zhiyong Fan, Cimin Long, Yonghui Chen, Jinping Deng and Wu Xin*, 2014. Expressions of HSPs mRNA in Different Tissues of Sows During Late Gestation Stage in Thermal Environment. Journal of Animal and Veterinary Advances, 13: 531-537. 54.Zheng Ruan, Shiqiang Liu, Yan Zhou, Shumei Mi, Gang Liu, Xin Wu, Kang Yao, Houssein Assaad, Zeyuan Deng, Yongqing Hou, Guoyao Wu, Yulong Yin. Chlorogenic Acid Decreases Intestinal Permeability and Increases Expression of Intestinal Tight Junction Proteins in Weaned Rats Challenged with LPS. PLoS ONE. 2014, 9(6):e97815 55.Duan J, Yin J, Wu M, Liao P, Deng D, Liu G, Wen Q, Wang Y, Qiu W, Liu Y, Wu X, Ren W, Tan B, Chen M, Xiao H, Wu L, Li T, Nyachoti CM, Adeola O, Yin Y. Dietary glutamate supplementation ameliorates mycotoxin-induced abnormalities in the intestinal structure and expression of amino acid transporters in young pigs. PLoS One. 2014,18;9(11):e112357. 56.Zheng Ruan, Yuhui Yang, Yan Zhou, Yanmei Wen, Sheng Ding, Gang Liu, Xin Wu, Peng Liao, Zeyuan Deng, Houssein Assaad, Guoyao Wu, Yulong Yin. Metabolomic analysis of amino acid and energy metabolism in rats supplemented with chlorogenic acid. Amino Acids. 2014, 46(9):2219-2229 57.Xin Wu, Yuzhe Zhang, Yulong Yin, Guoyao Wu. Role of stress protein 70 in protecting against intestinal mucosal damage. FRONTIERS IN BIOSCIENCE, 2013, 18, 356-365 58.Xin Wu, Chunyan Xie, Yulong Yin, Fengna Li, Tiejun Li, Ruilin Huang, and Zeyuan Deng. Effect of L-arginine on HSP70 expression in liver in weanling piglets. BMC Veterinary Research, 2013, 9:63. 59.Wu Xin, XG Shu, Chunyan Xie, Jun Li, Jiang-Ning Hu, Yulong Yin, Ze-Yuan Deng. The acute and chronic effects of monosodium L-glutamate on serum iron and total iron-binding capacity in the jugular artery and vein of pigs. Biological Trace Element Research, 2013, 153(1-3): 191-195. 60.Xin Wu, Chunyan Xie, Yulong Yin, Ze-Yuan Deng. The results of some studies involving animal models of obesity induced by monosodium glutamate are not conclusive. 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