n 教育、进修经历 2020.6至今仲恺农业工程学院，化学化工学院，应化系，特聘副教授 2017.7-2020.5，南开大学化学学院，博士后。 2012.9-2017.6，中国农业大学化学系，获理学博士学位。 2008.9-2012.6，中国农业大学化学系，获理学学士学位。 n 代表性科研项目 1.广东省基础与应用基础研究基金青年基金，2020A1515111112，多取代吡唑衍生物的合成及其抑菌活性研究，2020/10-2023/09，10万元，在研，主持； 2.广州市基础与应用基础研究基金，202102020214，苯并噁嗪酮衍生物的合成及其抑菌活性研究，2021/04-2023/03月31日，5万元，在研，主持； 3.参与国家自然科学基金项目“ 天然源稠三环螺内酯的抗植物病毒作用机制及其先导优化”(批准号：31872007), 2019年1月-2022年12月 n 代表性论文、著作等 1. Dongyan Yang, Xin Qi, Xinhua Zhou, Zhengming Li, Hongjun Zhou* and Zhijin Fan*. Synthesis of Potent Antifungal 3,4-Dichloroisothiazole-Based Strobilurins with Both Direct Fungicidal Activity and Systemic Acquired Resistance. RSC Medicinal Chemistry, 2022, DOI: 10.1039/D1MD00402F 2. Dongyan Yang, Xin Qi, Tatiana A. Kalinina, Tatiana V. Glukhareva,Nailou Zhang, Zesheng Hao, Zhengming Li*, Zhijin Fan*. Synthesis of 1,2,3-Thiadiazole- and Isothiazole-Based Phenyl Substituted Pyridine Containing Carboxyamide as Potent Plant Elicitors. Pest Manag Sci. 2022; 78: 1138–1145 3. Dongyan Yang, Haixia Wang, Zhijin Fan*, Zhengming Li*, Shuang Zhou, Zesheng Hao, You Lv, Tatiana A. Kalinina, Tatiana V. Glukhareva*. Design, synthesis and antifungal activity of (E)-3-acyl-5-(methoxyimino)-1,5-dihydrobenzo[e][1,2]oxazepin-4(3H)-one analogues.Mol divers,2021,25:159–169. 4. Dongyan Yang, Bin Zhao, Zhijin Fan*, Bin Yu, Nailou Zhang, Zhengming Li*, Yilin Zhu, Jinghui Zhou, Tatiana A. Kalinina, Tatiana V. Glukhareva. Synthesis and biological activity of novel succinate dehydrogenase inhibitor derivatives as potent fungicide candidates. J. Agric. Food Chem. 2019, 67(47): 13185-13194. 5.Dongyan Yang, Chuan Wan, Yumei Xiao, Chuanliang Che, Changhui Rui, Zhaohai Qin*.Design,synthesis, andinsecticidalactivity ofnovel 1-alkoxy-2-nitroguanidines. RSC adv. 2018,8,1838-1845. 6. Dongyan Yang, Chuan Wan, Mengmeng He, Chuanliang Che, Yumei Xiao, Bin Fu,Zhaohai Qin*. Design, synthesis, crystal structure and fungicidal activity of (E)-5-(methoxyimino)-3,5-dihydrobenzo[e][1,2]oxazepin-4(1H)-one analogues. MedChemComm. 2017, 8, 1007-1014. 7. Dongyan Yang, Lei Wang, Changqing Jia, Changsheng Li, Yongqiang Ma*,Changhui Rui, Yanjun Xu, Zhaohai Qin*.Syntheses andinsecticidalactivities ofnitro arylideneaminoguanidinederivatives.Chem J Chinese U, 2014, 35(8):1703-1709 8. Chuan Wan #,Dongyan Yang#, Ruiyuan Liu,Huizhe Lu*,Chuanliang Che,Yanjun Xu,Xueqin Zhang,Yumei Xiao,Jia-Qi Li, Zhaohai Qin*. 1’-OH of ABA and its analogs is a crucial functional group correspondence to seed germination and development of plants. Journal of Molecular Structure, 2022,1249,131650.(Equally contributed as first author) 9.Rui Wang#, Dongyan Yang#,Tian Tian,Yuhao An,Chuan Wan, Qi Chang, Mingchan Liang, Zhanfeng Hou, Ying Wang, Liang Zhang*, Zigang Li*.Low-toxicity Sulfonium-based Probes for Cysteine-specific Profiling in Live Cells. Analytical Chemistry.2022, 94, 4366−4372. (Equally contributed as first author) 10. Yong Xu#, Dongyan Yang#, Xianggao Zou, Changhui Rui, ZiyuanZhou, Yongqiang Ma,Zhaohai Qin*. Design,synthesis andinsecticidalactivity ofnovelhydrocarbylidenenitrohydrazinecarboximidamides. Pest Manag Sci. 2017,73,1927-1934. (Equally contributed as first author) 11. Xuelian Liu#,Dongyan Yang#, Fahong Yin, Jia-Qi Li, Yumei Xiao, Bin Fu,Zhaohai Qin. The application of “plug-in molecules” method in novel strobilurin fungicides screening.RSC Adv., 2020, 10, 42804–42809 (Equally contributed as first author) 12. 杜士杰#,杨冬燕#,万川,赵峰海,覃兆海.新型芳氧吡啶肟醚类化合物的设计、合成和杀虫活性,农药学学报，2021, 23(3): 476-482(Equally contributed as first author) 13. Bin Yu, Bin Zhao, Zesheng Hao, Lei Chen, Lixin Cao, Xiaofeng Guo*, Nailou Zhang,Dongyan Yang*, Liangfu Tang, Zhijin Fan*. Design, synthesis and biological evaluation of pyrazole-aromatic containing carboxamides as potent SDH inhibitors. Eur J Med Chem, 2021,214, 113230. 14.Nailou Zhang, Shuang Zhou,Dongyan Yang*, Zhijin Fan*. Revealing Shared and Distinct Genes Responding to JA and SA Signaling in Arabidopsis by Meta-Analysis.Front. Plant Sci.2020, 11, 113230. 15. Bin Zhao, Haixia Wang, Zhijin Fan*, Qifan Wu, Xiaofeng Guo, Nailou Zhang,Dongyan Yang,* Bin Yu, Shuang Zhou. Mode of action for a new potential fungicide candidate,3-(4-Methyl-1,2,3-thiadiazolyl)-6-trichloromethyl-[1,2,4]-triazolo-[3,4-b][1,3,4]-thiadiazole by iTRAQ. Food Agr.Immunol. 2019, 30, 1, 533-547. 16. Xiaofeng Guo,Dongyan Yang*, Zhijin Fan*, Nailou Zhang, Bin Zhao, Chun Huang, Fangjie Wang, Rongji Ma, Meng Meng*, and Youcai Deng*, Discovery and structure-activity relationship of novel diphenylthiazole derivatives as BTK inhibitor with potent activity against B cell lymphoma cell lines. Eur. J. Med. Chem. 2019, 178, 767-781. 17.Bin Zhao, Sijia Fan, Zhijin Fan*, Haixia Wang, Nailou Zhang, Xiaofeng Guo,Dongyan Yang*, Qi Fan Wu, Bin Yu, Shuang Zhou. Discovery of pyruvate kinase as a novel target of new fungicide candidate 3-(4-methyl-1,2,3-thiadiazolyl)-6-trichloromethyl-[1,2,4]-triazolo-[3,4-b][1,3,4]- thiadiazole. J. Agric. Food Chem., 2018, 66(28): 12439-12452. 18.Qifan Wu, Bin Zhao, Zhijin Fan*, Jiabao Zhao, Xiaofeng Guo,Dongyan Yang,* Nailou Zhang, Bin Yu, Tatiana Kalinina* and Tatiana Glukhareva. Design, synthesis and fungicidal activity of isothiazole-thiazole derivatives. RSC Adv., 2018, 8(69): 39593-39601. 19. 参与编写学术专著《植物免疫诱导技术》（字数4 0 .3万）科学出版社 n 教学科研获奖情况 1.高活性亚胺基苯乙酸酯类化合物及其制备方法和应用，授权公告号：CN 106946770 B. 2.高活性N-烃氧基新烟碱类似物及其制备方法和应用，授权公告号：CN 106632132 B. |
